Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids.
We examined the in vivo behavior of liver natural killer T cells (NKT cells) by intravital fluorescence microscopic imaging of mice in which a green fluorescent protein cDNA was used to replace the gene encoding the chemokine receptor CXCR6.NKT cells, which account for most CXCR6(+) cells in liver, were found to crawl within hepatic sinusoids click